Analysis of combined effects of benzene with radiation on chromosomes in cultured human leukocytes. Morimoto K.

http://www.ncbi.nlm.nih.gov/pubmed/1035661

Sangyo Igaku. 1976 Jan;18(1):23-34.
Analysis of combined effects of benzene with radiation on chromosomes in cultured human leukocytes.
Morimoto K.
Abstract
Three experiments were carried out on 53-hr cultured human leukocytes on chromosome mutagenicity of benzene with particular reference to combined effects with gamma-radiation and inhibitory effect on rejoining of radiation-induced chromosome breaks. The results and their analyses were summarized as follows: 1) Benzene can induce mainly chromatid-type deletions, especially gaps, suggesting that the cells in their late S-G2 stage have a higher susceptibility to chromosome breakage by benzene. 2) The aberration tield of dicentrics and rings induced by 100 rads irradiation can significantly be enhanced by the treatment of benzene equal to or in excess of 0.2 mM. 3) Quantitative analyses using newly defined “Synergetic effect factor” revealed that combined cytogenetic
effect of benzene with radiation could be synergetic exclusively in dicentrics and rings, being almost additive in the other types of aberration. 4) The experiment with dosage fractionation method showed that the more strongly benzene could inhibit the rejoining of radiation-induced chromosome breaks, the higher concentration it was treated at. Related iwth these results, possible inducps, and the repair and its inhibition of radiation-induced DNA-strand(s) breaks. Further studies for related effects by benzene are needed on protein synthesis, activities of repair enzymes and fine structure of chromosomes.
PMID: 1035661 [PubMed – indexed for MEDLINE]

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“Not our fault” says the petro chemical industry

“Don’t blame us” says the nuclear industry.

The Western Lifestyle.

Eat Cesium, its like a banana says the Japanese government.

No its effing not.

One Response to “Analysis of combined effects of benzene with radiation on chromosomes in cultured human leukocytes. Morimoto K.”

  1. CaptD Says:

    To those that think more about profits than health some additional radiation is no big deal; especially when it is other peoples dosage they are talking about!

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