Effects of Nuclear Fallout. Diseases other than malignancy

Deaths due to non-cancer disease
Analyses of the Life Span Study (LSS) mortality data (1950-1997) show a statistically significant dose-response pattern for death from diseases other than cancer. The excess does not seem limited to any particular disease. Among the 49,114 LSS survivors with colon doses of at least 0.005 Gy (DS86), 18,049 non-cancer deaths occurred (excluding deaths attributed to diseases of the blood). Circulatory diseases account for nearly 60% of these deaths, with digestive diseases, including liver diseases, and respiratory diseases accounting for about 15% and 10%, respectively.

Aside from diseases of the blood, the number of excess non-cancer deaths associated with A-bomb exposure is estimated at 150 to 300 cases. The death rate following exposure to 0.2 Gy (the mean radiation dose for the 49,114 survivors with doses >0.005 Gy) is increased by about 3% over normal rates. This is less than the death rate increase for solid cancers, where corresponding increases are 7% in men and 12% in women (age 30 ATB). The dose-response pattern is still quite uncertain (Figure 1).

Figure 1. Non-cancer dose-response function for the period 1968-1997 (DS86). The solid straight
line indicates the fitted linear ERR model without any effect modification by age at exposure,
sex or attained age. The points are dose category-specific ERR estimates, the solid
curve is a smoothed estimate derived from the points, and the dashed lines
indicate upper and lower one-standard-error bounds on the smoothed
estimate. The right panel shows the low-dose portion of the
dose-response function in more detail.

A significant radiation dose-response pattern was also seen for non-cancer blood diseases. Such diseases were studied separately since they may represent various hematologic malignant or premalignant conditions. Among the 128 deaths for which medical records were available and in which hematologic reviews were performed, about 45% were clearly classified as non-neoplastic blood diseases, 6% were diagnosed as leukemia or other hematopoietic cancers, and the remainder were potentially preneoplastic.

In the absence of known biological mechanisms, it is important to consider whether these results might be due to biases or to diagnostic misclassification of cancer deaths. Investigations have suggested that neither of these factors can fully explain the findings, especially for circulatory diseases that have been investigated more fully.

The Adult Health Study (AHS) incidence studies of non-cancer diseases show relationships with A-bomb dose for benign uterine tumors, thyroid disease (e.g., thyroid nodules), chronic liver disease, cataract, and hypertension (Figure 2). The LSS mortality data also show dose-related excesses for respiratory diseases, stroke, and heart diseases (Figure 3).

Although the LSS data on heart disease mortality suggest that radiation is associated mainly with hypertensive and congestive heart disease, AHS data also suggest an association with myocardial infarction, as well as with a measure of atherosclerosis (aortic arch calcification). There is particular evidence, therefore, from both AHS clinical data and LSS mortality studies, that the rates of cardiovascular disease are increased in A-bomb survivors, especially, it appears, for persons exposed at young ages. Studies regarding possible underlying biological mechanisms are being conducted.

end quote.

http://www.publichealth.va.gov/exposures/radiation/diseases.asp

United States Department of Veterans Affairs

Other diseases associated with radiation exposure

If a Veteran who was exposed to radiation during military service (including “Atomic Veterans”) develops one of the diseases listed below and meets other requirements, disability compensation may be provided on a case-by-case basis.

All cancers
Non-malignant thyroid nodular disease
Parathyroid adenoma
Posterior subcapsular cataracts
Tumors of the brain and central nervous system

Eligibility depends on how much radiation the Veteran received and other factors, such as the period of time between exposure to radiation and the development of the disease.

end quote
(A parathyroid adenoma is a benign tumor of the parathyroid gland. It can cause hyperparathyroidism.)

I think perhaps a closer look at survivors of the World Warnot cancer 2 atomic bombings, the survivors of Chernobyl, the survivors of Mercury Nuclear test site USA and others require a closer look in order to investigate the medical consequences of exposure to nuclear radiation and nuclear fallout as a vector.

http://en.wikipedia.org/wiki/Chernobyl_Children%27s_Project_%28UK%29

Chernobyl Children’s Project (UK)

Chernobyl Children’s Project (UK) is a UK registered charity based in Glossop, Derbyshire. The charity brings children to the UK for recuperative holidays; many of the children are in remission from cancer or suffer from chronic conditions such as epilepsy or diabetes.[1]

CCP (UK) was founded in 1995 by Linda Walker, who began by organising local groups to host children during the summer. It soon became apparent that holidays weren’t enough, and problems within Belarus were affecting lives of thousands of children and young adults with disabilities. Nowadays, the charity oversees many projects with the help of their Belarusian partners, Supporting Children Together. These include:

Funding extra carers in institutions for children and adults with disabilities
Running an independent living scheme for 5 young adults
Running a family style home for 4 children with disabilities
Coordinating an extensive training and educational programme to support children when they leave care, find foster families, get children back with their families and generally promote a positive attitude towards disability with the aim of deinstitutionalisation.
Respite care for children living with families
Supporting children with cancer by funding medicines and extra support
Supporting the hospice in Minsk and coordinating a home hospice team in Gomel region

The charity’s regional groups raise funds and organise recuperative holidays for children with health problems or who are in remission from cancer and those who live in contaminated parts of Belarus. They are great advocates for the charity and all the work being done in Belarus.

http://www.chernobyl-children.org.uk/archives/6129

One Response to “Effects of Nuclear Fallout. Diseases other than malignancy”

  1. CaptD Says:

    More of these will be needed in Japan as time proves that Fukushima was much worse than what the Japanese Government said it was… :-0

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