Latency of Childhood Thyroid Cancer

Nat Clin Pract Endocrinol Metab. 2007 May;3(5):422-9.
Mechanisms of Disease: molecular genetics of childhood thyroid cancers.
Yamashita S, Saenko V.

Department of Molecular Medicine, Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Sciences, Japan.

Childhood thyroid cancers are uncommon and have a fairly good prognosis. Papillary adenocarcinoma is the most prevalent malignant tumor of the thyroid in children and adults with radiation-induced or sporadic cancer. The incidence of thyroid cancer in children increased dramatically in the territories affected by the Chernobyl nuclear accident; this increase is probably attributable to (131)I and other short-lived isotopes of iodine released into the environment. There was a broad range of latency periods in children who developed thyroid cancer; some periods were less than 5 years.

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